Preparation of E 2,4-Diclorophenyl 1- phenyl propenone Abstract In this experiment E 2,4-Diclorophenyl 1-phenyl propenone was formed using a the aldol condensation reaction. Then the adduct was collected to figure the percent yield. The percent yield I calculated was Introduction In order to produce a resonance stabilized unsaturated ketone a crossed aldol condensation reaction is used so that the intermediate can undergo dehydration.
Also, the product is complex enough that it is not named here. Many compounds with benzene rings in the structure are referred to by their common names rather Aldol lab the IUPAC name as the common name is simpler. In this reaction you will be crushing the two solid reactants together.
As they mix they will have their melting points will lower colligative properties and at some point they will become a gummy liquid or oil. As you continue to mix the reactants, now with a catalyst added, the reaction will continue to take place and a new solid will form.
Once the reaction is complete there will only be solid present. You will then be able to evaluate the purity of that solid based off the melting range. Greening the Chemistry This experiment demonstrates three green principles. First this reaction demonstrates excellent atom economy.
Atom economy is a comparison evaluating how many atoms in the reactants end up in the product. In our reaction, all the atoms in the reactants go into the desired product except for two hydrogen and one oxygen Aldol lab.
This is an extremely efficient reaction, or as we say, has high atom economy. The atoms not going into the desired product form water — not bad as waste goes.
Secondly this reaction is also carried out without a solvent. As you will see throughout this year, most reactions use solvents. Solvents are a significant component of industrial chemical waste. Making a reaction solventless significantly reduces chemical waste.
Thirdly this reaction uses sodium hydroxide as a catalyst. A catalyst increases the rate of reaction, without being consumed by the reaction, allowing a small amount of catalyst to be recycled many times within a reaction.
The catalyst does react during this process but is regenerated before the product is formed allowing it to react again and again. Avoid contact with the NaOH as it is caustic. Wear gloves when doing this experiment. Using weighing paper, weigh 0. Crush and scrape the two solids together with a metal spatula until they become a darkly colored oil.
Once the oil has formed add 0. Continue mixing and scraping until the mixture becomes solid.
Let the mixture stand for 15 minutes to allow the reaction to come to a stop. Weigh to the accuracy of your balance. The more places you have the more accurate you can calculate your yield. Be patient with the mixing as the mixing will take some time.
Note that pressing harder will not speed the process, but may break the beaker. Scrape the beaker thoroughly to make sure that all the solid is mixed with the solution. Check the pH of the solution by dipping your spatula in the solution and then touching it to the pH paper.
Confirm that the solution is acidic, if not add more acid and mix again.
Collect the product using vacuum filtration. Draw air through the product for a few minutes to help dry the product and then dry the product for an additional 15 minutes in the drying oven.
Determine the mass of your crude product and calculate a percent yield. Take a small sample of pure 3,4-dimethoxybenzaldehyde and a small sample of 1-indanone and determine their melting points. Determine the melting range of your product.Aldol Condensation.
In some cases, the adducts obtained from the Aldol Addition can easily be converted (in situ) to α,β-unsaturated carbonyl compounds, either thermally or under acidic or basic leslutinsduphoenix.com formation of the conjugated system is the driving force for this spontaneous dehydration.
In aldol condensation, an enolate ion reacts with another carbonyl compound to form a conjugated enone. The process occurs in two parts: an aldol reaction, which forms an aldol product, and a dehydration reaction, which removes water to form the final product. Michael/Aldol product to make starting from either 4-chlorobenzaldehyde, 4-methoxybnezaldehdye, 4- methylbenzaldehyde or piperonaldehyde (your choice). Specific comments on Experiment Note that p-anisaldehyde is the same as Mixed Aldol (lab 8) STUDY. PLAY. The reaction of an aldehyde with a ketone using sodium hydroxide as the base is an example of what type of reaction? mixed aldol condensation reaction (aka Claisen-Schmidt reaction) Claisen-Schmidt (in general).
In aldol condensation, an enolate ion reacts with another carbonyl compound to form a conjugated enone. The process occurs in two parts: an aldol reaction, which forms an aldol product, and a dehydration reaction, which removes water to form the final product.
The preparation of dibenzalacetone (1,5-diphenyl-1,4-pentadienone) is an example of an aldol condensation in which the ketone, acetone, possesses two sets, albeit equivalent, of alpha-hydrogens.
The Aldol Reaction and Condensation The reaction of carbonyl compound enolates with aldehydes and ketones to form a β-hydroxy carbonyl compound is the Aldol Reaction, if conditions result in a subsequent dehydration to form the α,β-unsaturated compound, then the reaction is termed the Aldol Condensation (loss of a molecule of .
Lab Aldol Condensation. STUDY. PLAY. What is condensation? reaction between two or more molecules that leads to the formation of a larger molecule and an elimination of a smaller molecule (usually water) What kinds of compounds undergo aldol condensation?
carbonyl-containing compounds. Experiment 23 – The Aldol Condensation Page 1 of 4 The Aldol Condensation: Synthesis of Dibenzalacetone A.
Introduction In an aldol condensation, two molecules of aldehyde or ketone are joined together along with.